A city is ravaged by an epidemic of 'white blindness.' Those first afflicted are quarantined by the authorities in an abandoned mental hospital where societal norms quickly breaks down. Criminals and the physically powerful prey upon the weak, hording the meager food rations and committing horrific acts. Inside the hospital is one eyewitness to the nightmare. Following her husband into the hospital, a woman whose sight is unaffected by the plague goes into quarantine. There, keeping her sight a secret, she guides seven strangers who have become like a family. She leads them out of quarantine and onto the ravaged streets of the city. Their voyage is fraught with danger, but their survival is a reflection of the depth of the human spirit.